416 Milk Components as a Tool in Predicting Tolerance in Cowʼs Milk Allergy

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416 Milk Components as a Tool in Predicting Tolerance in Cow's Milk Allergy

investigated by immunoblot with serum from individuals sensitized to anisakis or shrimp. IgE binding patterns in the immunoblots were used for the identification of major Anisakis allergens, which were analysed by mass spectrometry-based proteomics in ESI-Orbitrap, after separation on SDS-gel. Results: Four new allergen candidates were identified. The first identified allergen was enolase, whic...

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Debates in allergy medicine: baked egg and milk do not accelerate tolerance to egg and milk

There is emerging evidence that children with egg and cow's milk allergy who can tolerate these allergens cooked in baked goods are more likely to develop tolerance. As a result a hypothesis has arisen that exposure to egg and milk in baked goods may hasten tolerance development; however, it is unclear whether children who develop tolerance do so because they have ingested low levels of egg or ...

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Adequacy and tolerance to ass's milk in an Italian cohort of children with cow's milk allergy

BACKGROUND The therapy for cow's milk proteins allergy (CMPA) consists in eliminating cow's milk proteins (CMP) from the child's diet. Ass's milk (AM) has been recently considered as substitute of CMP. This prospective study investigated tolerance and nutritional adequacy of AM in children with CMPA from Southern Italy. METHODS Thirty children (aged 6 months to 11 years) with suspected CMPA w...

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Cow's milk protein allergy: immunological response in children with cow's milk protein tolerance.

OBJECTIVE To study changes in immunological responses in patients with CMPA during symptomatic and asymptomatic episodes of cow's milk protein tolerance status. METHODS 27 CMPA patients were enrolled and underwent diagnostic evaluation, including CM challenge test, skin prick test and specific IgE to CM. Blood samples were collected in two periods from those who became tolerant (n = 13) and t...

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Tolerance to extensively heated milk in children with cow's milk allergy.

BACKGROUND Cow's milk allergy is the most common childhood food allergy. Previously we noted that children who outgrew their milk allergy had milk-specific IgE antibodies primarily directed against conformational epitopes; those with persistent milk allergy also had IgE antibodies directed against specific sequential epitopes. OBJECTIVE Because high temperature largely destroys conformational...

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ژورنال

عنوان ژورنال: World Allergy Organization Journal

سال: 2012

ISSN: 1939-4551

DOI: 10.1097/01.wox.0000412179.87263.bd